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5,508 episodes · 33 shows
Audio unavailableS2E45: Ep 45 Drugs & Genes: Pharmacogenetics and Pathology
One of the important jobs of a doctor is to prescribe medications. Unfortunately, it also happens to be one of the most challenging. Pharmacokinetics, physiology, and drug-to-drug interactions are just some of the challenges that doctors de…
Audio unavailableS2E44: Ep 44 Will not have been meaningless | PKU & Cystic Fibrosis Pathology
In the 1920’s, Pearl Buck searched for an answer to her 3 year old daughters intellectually disability. Unfortunately, no-one could help her because her daughter's condition was not yet known. From the mid 1930s to the 1960s, a remarkable s…
Audio unavailableS2E43: Ep 43 Engineering Einstein | Digital Pathology & Artificial intelligence
The computing world has come a long way in less than 100 years. Since Alan Turing introduced his paper ‘Computing Machinery and Intelligence’ in 1950, we have not only achieved the ‘Turing Test’ of Artificial Intelligence, but exceeded it. …
Audio unavailableS2E43: Ep 42 The Cholesterol Conundrum | Pathology
Cholesterol is an essential component of our cells. It is synthesized by our cells and affected by dietary, lifestyle, and genetic factors. Unfortunately, cholesterol for doctors can feel like a moving target as different guidelines have di…
Audio unavailableS2E41: Ep 41 Napoleon | The Bonaparte Conspiracy & Gastric cancer pathology
“I die before my time, killed by the Englisholigarchyand its hired assassins.” These are the words of Napoleon Bonaparte dictated in his last will and testament on his death bed. Napoleon is undoubtedly one of the world’s greatest Generals.…
Audio unavailableS2E40: Ep 40 Multiple Endocrine Neoplasia (M.E.N.) Pathology | Genetic Puzzles
Multiple Endocrine Neoplasia is a difficult diagnosis for patients, families, and clinicians. The vast array of symptoms, affected organs, and complex genetics often mean that it can take years (if not longer) for it to be diagnosed. In add…
Audio unavailableS2E39: E39 Coeliac disease and pathology | Slag om Gluten (Dutch)
Coeliac disease has been recognised since the times of Ancient Greece. This is a malabsorption disease that causes abdominal pain, nausea, vomiting, bloating, diarrhoea, and leaves sufferers starved of nutrients. The offending protein is Gl…
Audio unavailableS2E38: Ep 38 Leprosy and Pathology | From tzaraat to leprosy
Leprosy the disease, is rife with myths and false beliefs. In 1863, Hawaii recognised leprosy an official public health threat. In 1865, a law of segregation was enacted forcing sufferers to Kalaupapa on Molokai island. As fate would have i…
Audio unavailableS2E37: Episode 37: Lead Pathology | Saturn’s sweet poison
Lead has been used for thousands of years. And why not? This is a metal that is abundant, pliable, has a low melting point, and does not easily corrode. However, even our ancestors knew that those who worked closely with it often became sic…
Audio unavailableS2E36: Ep 36 HIV | Defenceless
In June 1981, the CDC reported an article of 5 men who presented with Pneumocystis pneumonia (PCP). PCP is an opportunistic infection more commonly found immunosuppressed patients (ie. patients receiving chemotherapy for cancer). The 5 men …
Audio unavailableS2E35: Ep 35 Piercing the smoke screen | Cigarettes, Smoking & Vapes
The rise of the tobacco industry and prevalence of smoking has significantly shaped the health (or lack of) in the last century. In 1900s, lung cancer was rare. 60 years later, it was the top cause of cancer deaths in men and second in wome…
Audio unavailableS2E34: Ep 24 Hodgkin Lymphoma | Almost Lardaceous Disease
Hodgkin Lymphoma, formerly known as Hodgkin disease, is a cancer of the lymph node(s). First described by Thomas Hodgkin (1832) where he wrote a paper titled ‘On Some Morbid Appearances of the Absorbent (now Lymphatic) Glands and Spleen’. H…
Audio unavailableS2E33: Ep 33 | Fragile X: The Fra(X)-men
Fragile X is the most common form of inherited intellectually disability. It is a sex-linked chromosomal disorder that affects boys much more commonly than girls. However, it took some ingenious foresight combined with advancing genetic tec…
Audio unavailableS2E32: Ep 32 | The Social Media Literati
Information in the past (ergo knowledge) was restricted to the few. However, the social media landscape provides individuals with their personal megaphone to the world. As most are aware, there are numerous benefits this provides, such as e…
Audio unavailableS2E31: Ep 31 Allergies Part Two | Anaphylaxis and Fighting Food
In 1901, an experiment when horribly wrong when Doctors attempted to induce tolerance in to a group of dogs by repeated injections of poison. The results were reproducible. Furthermore, the substance did not even need to be poisonous. In 19…
Audio unavailableS2E30: Ep 30 Allergies Part One | Friendly Fire
Our immune system provides the means for us to live in a world full of pathogens.However, sometimes it gets it wrong and we can find ourselves debilitated because of our own immune system.Allergies and hypersensitivies fall into this catego…
Audio unavailableS2E29: CST Cervical Screening | A smear in time (saves lives)
In 1952, George Papanicolaou with the National Cancer Institute embarked on the first ever cervical screening trial.The results were remarkable and the first demonstration of the power of screening an asymptomatic population. However, the p…
Audio unavailableS2E28: Ep 28 | Data MyHealthRecord | Data Deep Dive
Health records are arguably the single most important and personal collection of data anyone can have. With records containing doctor visits, consultation notes, pathology results, radiology reports, medications, allergies, etc., it is hard…
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S2E27: Ep 27 Coronavirus SARS-CoV-2 | Covidity 2021
COVID-19: Testing the strength of nations As the pandemic continues to rage, we take a snapshot in time about our current understanding from an epidemiological, pathological, microbiological and immunological viewpoint of COVID-19. This pan…
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S2E26: Ep 26 Indigenous Health | A Tale of Two Worlds
Caitlan Davis starts Episode 26 with, "In the spirit of reconciliation Clinpath Pathology acknowledges the Traditional Custodians of country throughout Australia and their connections to land, sea and community. We pay our respect to their …
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S1E25: Ep 25 The 12 Podcasts of Christmas
From our first Episode #1 "What is Pathology?", we have enjoyed the journey we have travelled and feedback to date is encouraging. In these times, remaining connected is as important as ongoing education and from here at Clinpath, providing…
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S1E24: Ep 24 Radiation | Invisible death
The discovery of radiation was a monumental achievement in human history. Marie Curie isolated Radium and Polonium from the mineral pitchblende, and received two Nobel Prizes for this achievement (Physics 1903 and Chemistry 1911). She was c…
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S1E23: Ep 23 Health IT Security | Avoiding the flat line
The implications for Healthcare to lose control or access to the IT systems is literally life threatening. The first confirmed fatality occurred when a Ransomware attack unintentionally struck a German University Hospital in September 2020.…
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S1E22: Ep 22 Drugs of Addiction | Medicinal binds
Humans have always had a complex relationship with drugs: some help us; some heal us; and some hurt us. The problem with the drugs of addiction is they can do all of three. However, long term use of these inevitably leads to dependence wher…